Prelimbic medial prefrontal cortex disruption during adolescence increases susceptibility to helpless behavior in adult rats
نویسندگان
چکیده
منابع مشابه
prelimbic of medial prefrontal cortex GABA modulation through testosterone on spatial learning and memory
Prefrontal cortex (PFC) is involved in multiple functions including attentional , spatial orientation, short and long-term memory. Our previous study indicated that microinjection of testosterone in CA1 impaired spatial learning and memory. Some evidence suggests that impairment effect of testosterone is mediated by GABAergic system. In the present study, we investigated the interaction of test...
متن کاملprelimbic of medial prefrontal cortex GABA modulation through testosterone on spatial learning and memory
Prefrontal cortex (PFC) is involved in multiple functions including attentional , spatial orientation, short and long-term memory. Our previous study indicated that microinjection of testosterone in CA1 impaired spatial learning and memory. Some evidence suggests that impairment effect of testosterone is mediated by GABAergic system. In the present study, we investigated the interaction of test...
متن کاملChronic Ritalin Administration during Adulthood Increases Serotonin Pool in Rat Medial Frontal Cortex
Background: Ritalin has high tendency to be abused. It has been the main indication to control attention deficit hyperactivity disorder. The college students may seek for it to improve their memory, decrease the need for sleep (especially during exams), which at least partially, can be related to serotonergic system. Therefore, it seems worthy to evaluate the effect of Ritalin intake on mature ...
متن کاملPrelimbic and Infralimbic Prefrontal Cortex Interact during Fast Network Oscillations
BACKGROUND The medial prefrontal cortex has been implicated in a variety of cognitive and executive processes such as decision making and working memory. The medial prefrontal cortex of rodents consists of several areas including the prelimbic and infralimbic cortex that are thought to be involved in different aspects of cognitive performance. Despite the distinct roles in cognitive behavior th...
متن کاملDnmt3a in the Medial Prefrontal Cortex Regulates Anxiety-Like Behavior in Adult Mice.
Recently, it has been suggested that alterations in DNA methylation mediate the molecular changes and psychopathologies that can occur following trauma. Despite the abundance of DNA methyltransferases (Dnmts) in the brain, which are responsible for catalyzing DNA methylation, their roles in behavioral regulation and in response to stressful challenges remain poorly understood. Here, we demonstr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Neuropsychopharmacology
سال: 2020
ISSN: 0924-977X
DOI: 10.1016/j.euroneuro.2020.04.004